WHO - World Health Organization officially recognizes Fluoride as a Low-Dose Endocrine Disruptor causing disease and excess Death.
How much do we know about Fluoride damage to your Hormones? These complex molecules secreted by your glands and organs in response to various stimuli have complex interrelationships and are vulnerable to toxins.
WHO states that Deafness is caused by Fluoride.
Deafness caused by Fluoride has been investigated for over 60 years.
It has been suggested that the deafness associated with Fluorosis is caused by pressure on the Vestibulocochlear nerve, also known as the 8th Cranial Nerve, which conducts information from the ear to the brain.
The damaging pressure is thought to be caused by Fluoride causing calcification obstruction of the Internal Acoustic Meatus.
Ref: Rao ABN and Siddiqui AH. 1962 The Journal of Laryngology & Otology. 76(2):94-99 .
From the Conference: INBC 2017. International Conference on Neurology and Brain Disorders, Valencia, Spain, 26-28 June 2017
Scientists attended this international conference to present their work for peer assessment and speed communication of important discoveries. They were showing details of research on Brain Damage done by Fluoride studied at the molecular and cellular levels. Quote:
"Fluorine is a strong neurotoxin which can cause decrease in the intelligence quotient, problems with learning and concentration. The Extracellular Matrix (ECM) of the central nervous system serves as the environment for neurons and glial cells, and at the same time, it plays the role of a modifier of these cells. Changes in the structure and the functioning of synapses are caused by ECM enzymes. These enzymes, especially matrix metalloproteinases (MMPs), accompany both physiological processes, such as learning or memorizing, and pathological processes. Metalloproteinases 9 and 2 (MMP-9 and MMP-2) and inhibitor of metalloproteinases-3 and -2 (TIMP-3 and TIMP-2) seem to be particularly interesting. There is no data regarding the influence of fluorine on the expression of these enzymes and their inhibitors in the brain. In the research, the rats were exposed to sodium fluoride (50 mg/L) already in the prenatal period until they reached the age of three months. After this time, the hippocampus, prefrontal cortex, cerebellum, and striatum were collected. In all of the aforementioned structures, the expression of proteins MMP-9, MMP-2, TIMP-3 and TIMP-2 was carried out by means of ELISA, gene expression by RT real time PCR and immunolocalization by immunohistochemistry method and microscopy visualization. On the basis of the results, it can be concluded that fluorine influences the expression of MMP-9, MMP-2, TIMP-3 and TIMP-2. In the study group, a statistically significant expression of MMP-2 was observed in the prefrontal cortex, striatum, and cerebellum, and a decrease in the expression of MMP-9 was noted in the prefrontal cortex and cerebellum in relation to the control group. We also saw the difference between TIMP-3 and TIMP-2 levels in study group compared to control. It could be suppose, that changes in expression of metalloproteinases and their inhibitors in brain, caused by fluorine, could be an important factor of neurotoxicity of fluorine. Disorder of neuroplasticity processes can be considered as a biochemical basis for decrease in the intelligence quotient caused by fluorine."
Changes in expression of metalloproteinase 2 and 9 and their inhibitors in the neurotoxic effects of fluoride. Available from: https://www.researchgate.net/publication/318339472_Changes_in_expression_of_metalloproteinase_2_and_9_and_their_inhibitors_in_the_neurotoxic_effects_of_fluoride
Water fluoridation has never been a safe, effective and ethical way to help reduce tooth decay. No peer-reviewed scientific proof with double-blind research, Evidence based only on statistical comparisons (=cherry-picked data) without taking confounding factors into account, like food, in particular sugar in the diet, toothbrushing practice and oral hygiene.
Asthma is not evenly distributed around the world and this map should make people interested enough to investigate how Fluoridation might be linked to this terrible affliction. Thanks to [NHMRC has removed third party information] for this snapshot. Understanding how your airways might be affected by Fluoride is essential because in hot climates Fluoridated water sprays generate highly concentrated aerosols of nanoparticles that penetrate to all corners of your lungs.
Townsville in Queensland, Australia and Fluoridated since 1964, suffers a higher rate of Trachea Cancer than the rest of Non-Fluoridated Queensland.
Fluoride mists can easily reach the tiniest structures of your lungs causing damage on contact. People living near Phosphate Fertilizer factories suffer lung disease caused by Hydrogen Fluoride.
WHO - World Health Organization - lists known respiratory harms of Fluoride including exacerbation of Asthma, Bronchitis, Chronic Cough, Chronic Obstructive Pulmonary Disease (COPD), and Lung Cancer. These harms arise through inhalation and drinking Fluoridated water. Cell death or Apoptosis has been well studied and is a primary cause of cancer.
Quote "NaF induces an apoptotic effect and an increase in PI-positive A549 cells via similar mechanisms, involving PKC, PKA, tyrosine kinase and Ca2+ linked enzymes".
http://journals.sagepub.com/doi/abs/10.1191/0960327103ht322oa?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed&
Understanding how your airways might be affected by Fluoride is essential because in hot climates Fluoridated water sprays generate highly concentrated aerosols of nanoparticles that penetrate to all corners of your lungs.
Townsville in Queensland, Australia and Fluoridated since 1964, suffers a higher rate of Trachea Cancer than the rest of Non-Fluoridated Queensland.
Fluoride mists can easily reach the tiniest structures of your lungs causing damage on contact. People living near Phosphate Fertilizer factories suffer lung diseaese caused by Hydrogen Fluoride.
Fluoride damages Your Stomach and Intestines
Reported symptoms of Fluoride ingestion include stomach haemmorrhage, nausea, vomiting, diarrhoea, and abdominal pain. This was all proven by Double Blind Placebo trials in the 1950s and 1960s. The Australian NHMRC continues to ignore the science, despite the application of the latest science that looks at the mechanisms. https://www.researchgate.net/publication/316375002_Enteric_innervation_combined_with_proteomics_for_the_evaluation_of_the_effects_of_chronic_fluoride_exposure_on_the_duodenum_of_rats_OPEN
Vets seem to know more about fluoride poisoning than GPs: http://www.msdvetmanual.com/toxicology/fluoride-poisoning/overview-of-fluoride-poisoning