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Draft NHMRC Information Paper: Effects of water fluoridation on dental and other health outcomes submission

ID: 
16
This submission reflects the views of
Organisation Name: 
Queenslanders for Safe Water Air and Food Inc
Personal Details
Specific Questions
Q1. B) Please provide details regarding your response to Question 1A: 
Q4. Is there additional evidence on the dental effects of water fluoridation that should be considered?: 

• Dental fluorosis: concentration of fluoride in drinking water and consumption of bottled beverages in school children
Author:Perez-Perez N, Torres-Mendoza N, Borges-Yanez A, Irigoyen-Camacho ME.
Journal Name:Journal of Clinical Pediatric Dentistry
Publish Date:Summer 2014
Volume/Page:38(4):338-44.
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Prevalence, Risk Factors, Total Body Burden, Sources of Exposure, Juice/Soda/Beer

• Evaluation of dental fluorosis in relation to DMFT rates in a fluorotic rural area of Turkey
Author:Kececi AD, Kaya BU, Guldas E, Saritekin E, Sener E.
Journal Name:Fluoride
Publish Date:April-June 2014
Volume/Page:47(2):119-32.
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Fluorosis/Caries Relationship

• Association between developmental defects of enamel and dental caries in schoolchildren
Author:Vargas-Ferreira F, Zeng J, Thomson WM, Peres MA, Demarco FF.
Journal Name:Journal of Dentistry
Publish Date:February 20, 2014
Volume/Page:[Epub ahead of print]
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Fluorosis/Caries Relationship

• Diffuse opacities in 12-year-old Hong Kong children – four cross-sectional surveys
Author:Wong HM, McGrath C, King NM.
Journal Name:Community Dentistry and Oral Epidemiology
Publish Date:February 2014
Volume/Page:42(1):61-9.
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Prevalence

• Dental caries and endemic dental fluorosis in rural communities, Minas Gerais, Brazil
Author:Costa de M, Abreu MH, Vargas AM, Vasconcelos M, Ferreira E, Castilho LS.
Journal Name:Revista Brasileira de Epidemiologia
Publish Date:December 2013
Volume/Page:16(4):1021-28.
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Fluorosis/Caries Relationship

• Aesthetic perceptions regarding fluorosis by children from an area of endemic fluorosis in India
Author:Jodalli PS, Ankola AV, Hebbal M, Vikneshan M.
Journal Name:Community Dental Health
Publish Date:December 2013
Volume/Page:30(4):249-53.
Type:Human Study
Categories:Dental Fluorosis, Cosmetic Damage

• Aesthetic management of dental fluorosis
Author:Khandelwal V, Nayak UA, Nayak PA, Ninawe N.
Journal Name:BMJ Case Reports
Publish Date:May 22 2013
Volume/Page:2013. pii: bcr2013010029.
Type:Human Study, Case Report
Categories:Dental Fluorosis, Cosmetic Treatment

• Agreement between parents and adolescents on dental fluorosis: a population-based study
Author:Almeida ME, Teixeira AK, Alencar CH, Paiva SM, Abreu MH.
Journal Name:Brazilian Oral Research
Publish Date:March 2013
Volume/Page:27(2):91-6
Type:Human Study
Categories:Dental Fluorosis

• Fluorosis and dental caries in Mexican schoolchildren residing in areas with different water fluoride concentrations and receiving fluoridated salt
Author:García-Pérez A, Irigoyen-Camacho ME, Borges-Yáñez A.
Journal Name:Caries Research
Publish Date:2013
Volume/Page:47(4):299-308.
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Fluorosis/Caries Relationship

• Etiological factors related to dental fluorosis among children in Poznan, Poland – a preliminary report.
Author:Opydo-Szymaczek J, Gerreth K.
Journal Name:Fluoride
Publish Date:October-December 2012
Volume/Page:45(4):337–342.
Type:Human Study
Categories:Dental Fluorosis, Susceptible Populations, Infant Formula/Foods, Sources of Exposure

• A national cross-sectional study on effects of fluoride-safe water supply on the prevalence of fluorosis in China
Author:Wang C, Gao Y, Wang W, Zhao L, Zhang W, Han H, Shi Y, Yu G, Sun D.
Journal Name:BMJ Open
Publish Date:September 25, 2012
Volume/Page:2(5).
Type:Human Study, Epidemiology
Categories:Bones/Joints, Skeletal Fluorosis, Dental Fluorosis, Total Body Burden, Tissue F Levels, Urine-F, Dose Response

• Comparison of dental esthetic perceptions of young adolescents and their parents
Author:Kavand G, Broffitt B, Levy SM, Warren JJ.
Journal Name:Journal of Public Health Dentistry
Publish Date:Spring 2012
Volume/Page:72(2):164-71
Type:Human Study
Categories:Dental Fluorosis, Cosmetic Damage

• Dental fluorosis, dental caries, and quality of life factors among schoolchildren in a Colombian fluorotic area
Author:Tellez M, Santamaria RM, Gomez J, Martignon S.
Journal Name:Community Dental Health
Publish Date:March 2012
Volume/Page:29(1):95-9
Type:Human Study
Categories:Dental Fluorosis, Cosmetic Damage

• Adolescents' perceptions of the aesthetic impact of dental fluorosis vs. other dental conditions in areas with and without water fluoridation
Author:McGrady MG, Ellwood RP, Goodwin M, Boothman N, Pretty IA.
Journal Name:BMC Oral Health
Publish Date:February 10, 2012
Volume/Page:12:4.
Type:Human Study
Categories:Dental Fluorosis, Cosmetic Damage

• Assessment of aesthetic perception of mild and moderate dental fluorosis levels among students from the Federal University of Minas Gerais-UFMG, Brazil
Author:Gleber-Netto FO, Diniz IM, Mudado FA, Fraga MG, Vargas AM.
Journal Name:Oral Health & Preventive Dentistry
Publish Date:2011
Volume/Page:9(4):339-45
Type:Human Study
Categories:Dental Fluorosis, Cosmetic Damage

• Relationship of caries and fluorosis in adolescents from high- and low-fluoride areas in Iran
Author:Meyer-Lueckel H, Bitter K, Khorrami G, Kielbassa AM, Paris S.
Journal Name:Community Dental Health
Publish Date:September 2011
Volume/Page:28(3):248-52.
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Fluorosis/Caries Relationship

• Perceptions of adolescents and young people regarding endemic dental fluorosis in a rural area of Brazil: psychosocial suffering
Author:de Castilho LS, e Ferreira EF, Perini E.
Journal Name:Health & Social Care in the Community
Publish Date:November 2009
Volume/Page:17(6):557-63
Type:Human Study
Categories:Dental Fluorosis, Cosmetic Damage

Diagnosing dental caries in populations with different levels of dental fluorosis
Author:Nyvad B, Machiulskiene V, Fejerskov O, Baelum V.
Journal Name:European Journal of Oral Cciences
Publish Date:April 2009
Volume/Page:117(2):161-8.
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Fluorosis/Caries Relationship, Prevalence

The impact of developmental defects of enamel on young people in the UK
Author:Marshman Z, Gibson B, Robinson PG.
Journal Name:Community Dentistry and Oral Epidemiology
Publish Date:February 2009
Volume/Page:37(1):45-57
Type:Human Study
Categories:Dental Fluorosis, Cosmetic Damage

A reaction-time study of social, health, and personal attributions in relation to fluorosed teeth.
Author:Bennett P, Williams D, Chestnutt I, Hood K, Lowe R.
Journal Name:Psychology, Health & Medicine
Publish Date:January 2008
Volume/Page:13(1):75-86.
Type:Human Study
Categories:Dental Fluorosis, Cosmetic Damage

Prevalence of Enamel Fluorosis Among 12-19 Year-Olds, U.S., 1999-2004.
Author:Beltran E, Barker L.
Journal Name:CONFERENCE: IADR/AADR/CADR 85th General Session and Exhibition
Publish Date:March 21-24, 2007
Type:Human Study
Categories:Dental Fluorosis, Prevalence

Relationship between dental caries experience (DMFS) and dental fluorosis in 12-year-old Puerto Ricans
Author:Elías-Boneta AR, Psoter W, Elías-Viera AE, Jiménez P, Toro C.
Journal Name:Community Dental Health
Publish Date:December 2006
Volume/Page:23(4):244-50.
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Fluorosis/Caries Relationship

Characteristics attributed to individuals with dental fluorosis
Author:Williams DM, Chestnutt IG, Bennett PD, Hood K, Lowe R.
Journal Name:Community Dental Health
Publish Date:December 2006
Volume/Page:23(4):209-16
Type:Human Study
Categories:Dental Fluorosis, Cosmetic Damage

• Caries and dental fluorosis in a western Saharan population of refugee children
Author:Almerich-Silla JM, Montiel-Company JM, Ruiz-Miravet A.
Journal Name:European Journal of Oral Sciences
Publish Date:December 2008
Volume/Page:116(6):512-7.
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Fluorosis/Caries Relationship

• Prevalence and severity of dental caries in adolescents aged 12 and 15 living in communities with various fluoride concentrations
Author:Pontigo-Loyola AP, Medina-Solis CE, Borges-Yañez SA, Patiño-Marín N, Islas-Márquez A, Maupome G.
Journal Name:Journal of Public Health Dentistry
Publish Date:Winter 2007
Volume/Page:67(1):8-13.
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Fluorosis/Caries Relationship

• Dental fluorosis in children in areas with fluoride-polluted air, high-fluoride water, and low-fluoride water as well as low-fluoride air: a study of deciduous and permanent teeth in the Shaanxi province, China.
Author:Ruan JP, Bardsen A, Astrøm AN, Huang RZ, Wang ZL, Bjorvatn K.
Journal Name:Acta Odontologica Scandinavica
Publish Date:April 2007
Volume/Page:65(2):65-71.
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Prevalence, Risk Factors, Total Body Burden, Sources of Exposure, coal, Inhalation exposure

Q5. Is there additional evidence on any other health effects of water fluoridation that should be considered in the draft Information Paper?: 

The first 2 listed papers ( on ADHD in USA by Malin and Till and on Hypothyroidism in UK were both published in Feb 2015 – the NHMRC draft information paper was published 14 September 2016 – the NHMRC had plenty of time to include, analyses and report - WHY WERE THESE TWO PAPERS NOT INCLUDED ??? The NHMRC must include an explanation in it’s final publications of why it ignored these papers in its draft information paper when every member of the NHMRC FRG would have known about them in Fen 2015
• Exposure to fluoridated water and attention deficit hyperactivity disorder prevalence among children and adolescents in the United States: an ecological association
Author: Malin AJ, Till C.
Journal Name:Environmental Health
Publish Date:February 27, 2015
Volume/Page:[Epub ahead of print]
Type:Human Study, Epidemiology
Categories:Brain, Behavior, Cognitive Function

• Are fluoride levels in drinking water associated with hypothyroidism prevalence in England? A large observational study of GP practice data and fluoride levels in drinking water
Author: Peckham S, Lowery D, Spencer S.
Journal Name:Journal of Epidemiology and Community Health
Publish Date:February 24, 2015
Volume/Page:[Epub ahead of print]
Type:Human Study, Epidemiology
Categories:Thyroid Gland, Thyroid Hormones

• Dietary fluoride intake and associated skeletal and dental fluorosis in school age children in rural Ethiopian Rift Valley
Author:Kebede A, Retta N, Abuye C, Whiting SJ, Kassaw M, Zeru T, Tessema M, Kjellevold M.
Journal Name:International Journal of Environmental Research and Public Health
Publish Date:July 26, 2016
Volume/Page:13(8).
Type:Human Study, Epidemiology
Categories:Bones/Joints, Skeletal Fluorosis, Susceptible Populations, Nutritional Status, Calcium

• Enzymatic activity of Glutathione S-Transferase and dental fluorosis among children receiving two different levels of naturally fluoridated water
Author:Bonola-Gallardo I, Irigoyen-Camacho ME, Vera-Robles L, Campero A, Gpmez-Quiroz L.
Journal Name:Biological Trace Element Research
Publish Date:July 23, 2016
Volume/Page:[Epub ahead of print]
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Mechanisms of Cellular Toxicity, Enzymes, Oxidative Stress

• Excessive fluoride consumption increases haematological alteration in subjects with iron deficiency, thalassaemia, and glucose-6-phosphate dehydrogenase (G-6-PD) deficiency
Author:Pornprasert S, Wanachantararak P, Kantawong F, Chamnanprai S, Kongpan C, Pienthai N, Yanola J, Duangmano S, Prasannarong M.
Journal Name:Environmental Geochemistry & Health
Publish Date:June 18, 2016
Volume/Page:[Epub ahead of print]
Type:Human Study, Epidemiology
Categories:Blood, Anemia

• Does fluoride affect serum testosterone and androgen binding protein with age-specificity? A population-based cross-sectional study in Chinese male farmers
Author:Duan L, Zhu J, Wang K, Zhou G, Yang Y, Cui L, Huang H, Cheng X, Ba Y.
Journal Name:Biological Trace Element Research
Publish Date:May 6, 2016
Volume/Page:[Epub ahead of print]
Type:Human Study, Epidemiology
Categories:Reproductive Toxicity, Testosterone

• Dental fluorosis and urinary fluoride concentration as a reflection of fluoride exposure and its impact on IQ level and BMI of children of Laxmisagar, Simlapal Block of Bankura District, W.B., India
Author:Das K, Mondal NK.
Journal Name:Environmental Monitoring and Assessment
Publish Date:April 2016
Volume/Page:188(4):218.
Type:Human Study, Epidemiology
Categories:Brain, Cognitive Function, IQ Score

• Refractive errors in Northern China between the residents with drinking water containing excessive fluorine and normal drinking water
Author:Bin G, Liu H, Zhao C, Zhou G, Ding X, Zhang N, Xu Y, Qi Y.
Journal Name:Biological Trace Element Research
Publish Date:February 27, 2016
Volume/Page:[Epub ahead of print]
Type:Human Study, Epidemiology
Categories:Eyes

• Association of dental and skeletal fluorosis with calcium intake and vitamin D concentrations in adolescents from a region endemic for fluorosis
Author:Kajale N, Patel P, Patel P, Patel A, Yagnik B, Mandlik R, Patwardhan V, Khadilkar V, Chiplonkar S, Mughal Z, Joshi P, Phanse-Gupte S, Khadilkar A.
Journal Name:Bone Abstracts
Publish Date:2015
Volume/Page:4:P62.
Type:Human Study, Epidemiology
Categories:Bones/Joints, Skeletal Fluorosis, Dental Fluorosis, Risk Factors, Susceptible Populations, Nutritional Status, Calcium,Vitamin D

• Fluoride exposure effects and dental fluorosis in children in Mexico City
Author:Molina-Frechero N, Gaona E, Angulo M, Sanchez Pérez L, Gonzalez Gonzalez R, Nevarez Rascon M, Bologna-Molina R.
Journal Name:Medical Science Monitor
Publish Date:November 26, 2015
Volume/Page:21:3664-70.
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Risk Factors, Total Body Burden, Sources of Exposure, Dental Products, Toothpaste

• Cognitive impairment and risk factors in elderly people living in fluorosis areas in China
Author:Li M, Gao Y, Cui J, Li Y, Li B, Liu Y, Sun J, Liu X, Liu H, Zhao L, Sun D.
Journal Name:Biological Trace Element Research
Publish Date:2016 [E pub Nov 25, 2015]
Volume/Page:[Epub ahead of print]
Type:Human Study, Epidemiology
Categories:Brain, Cognitive Function

• Collagenase 1A2 (COL1A2) gene A/C polymorphism in relation to severity of dental fluorosis
Author:Escobar-Garcia D, Mejia-Saavedra J, Jarquín-Yanez L, Molina-Frechero N, Pozos-Guillen A.
Journal Name:Community Dentistry & Oral Epidemiology
Publish Date:November 12, 2015
Volume/Page:[Epub ahead of print]
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, DF Mechanisms, Susceptible Populations, Genetics

• The research on the relationship between the ovarian function damage with fluorosis and the protective effect of selenium
Author:Chen Q, Wang ZL, Xiong YM, Liu D, Chen GX.
Journal Name:Value in Health
Publish Date:November 2015
Volume/Page:18(7):A638.
Type:Human Study, Epidemiology
Categories:Reproductive Toxicity, Ovary/Uterus

• Relationship between dental fluorosis and intelligence quotient of school going children in and around Lucknow district: a cross-sectional study
Author:Khan SA, Singh RK, Navit S, Chadha D, Johri N, Navit P, Sharma A, Bahuguna R.
Journal Name:Journal of Clinical & Diagnostic Research
Publish Date:November 2015
Volume/Page:9(11):ZC10-15.
Type:Human Study, Epidemiology
Categories:Brain, Cognitive Function, IQ Score

• Fluoride exposure, follicle stimulating hormone receptor gene polymorphism and hypothalamus-pituitary-ovarian axis hormones in chinese women
Author:Zhao MX, Zhou GY, Zhu JY, Gong B, Hou JX, Zhou T, Duan LJ, Ding Z, Cui LX, Ba Y.
Journal Name:Biomedical and Environmental Sciences
Publish Date:2015
Volume/Page:28(9):696-700.
Type:Human Study, Epidemiology
Categories:Reproductive Toxicity

• A cross-sectional study to assess the intelligence quotient (IQ) of school going children aged 10-12 years in villages of Mysore district, India with different fluoride levels
Author:Sebastian ST, Sunitha S.
Journal Name:Journal of the Indian Society of Pedodontics and Preventive Dentistry
Publish Date:October-December 2015
Volume/Page:33(4):307-11.
Type:Human Study, Epidemiology
Categories:Brain, Cognitive Function, IQ Score

• Nutritional status and dental fluorosis among schoolchildren in communities with different drinking water fluoride concentrations in a central region in Mexico
Author:Irigoyen-Camacho M.E., Garcia Perez A, Mejia Gonzalez A, Huizar Alvarez R.
Journal Name:Scient of the Total Environment
Publish Date:September 28, 2015
Volume/Page:541:512-519.
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Risk Factors, Susceptible Populations, Nutritional Status

• Evaluation of oxidative stress index in pregnant women exposed to fluoride (F-) in drinking water
Author:Rocha Amador D, et al.
Journal Name:Abstract of Presentation at 27th Conference of the International Society for Environmental Epidemiology
Publish Date:August 30 - September 3, 2015
Type:Human Study, Epidemiology
Categories:Mechanisms of Cellular Toxicity, Oxidative Stress

• Evaluation of thyroid hormones (TSH and T4) in pregnant women exposed to fluoride (F-) in drinking water
Author:Rocha Amador D, et al.
Journal Name:Abstract of Presentation at 27th Conference of the International Society for Environmental Epidemiology
Publish Date:August 30 - September 3, 2015
Type:Human Study, Epidemiology
Categories:Brain, Thyroid Gland, Thyroid Hormones

• Timing of fluoride intake and dental fluorosis on late-erupting permanent teeth
Author:Bhagavatula P, Levy SM, Broffitt B, Weber-Gasparoni K, Warren JJ.
Journal Name:Community Dentistry & Oral Epidemiology
Publish Date:July 22, 2015
Volume/Page:[Epub ahead of print]
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Risk Factors

• Effect of fluoride in drinking water on children’s intelligence in high and low fluoride areas of Delhi
Author:Kundu H, Basavaraj P, Singla A, Gupta R, Singh K, Jain S.
Journal Name:Journal of the Indian Association of Public Health Dentistry
Publish Date:2015
Volume/Page:13(2):116-121.
Type:Human Study, Epidemiology
Categories:Brain, Cognitive Function, IQ Score

• Thyroid dysfunction associated with excess fluoride intakes: scope for primary prevention
Author:Sachdeva S, Ahmed J, Singh B.
Journal Name:Thyroid Research & Practice
Publish Date:May-June 2015
Volume/Page:12(2):50-56.
Type:Human Study, Epidemiology
Categories:Thyroid Gland, Thyroid Hormones

• The relationship between Alu I polymorphisms in the calcitonin receptor gene and fluorosis endemic to Chongqing, China
Author:Jiang M, Mu L, Wang Y, Yan W, Jiao Y.
Journal Name:Medical Principles & Practice
Publish Date:2015
Volume/Page:24(1):80-3.
Type:Human Study, Epidemiology
Categories:Bones/Joints, Skeletal Fluorosis, Susceptible Populations, Genetics

• The impact of fluoride in drinking water on oral health and skeletal system of school children
Author:Meenakumari S, Mohan G, Sreelatha, Retnakumari N.
Journal Name:IOSR Journal of Dental and Medical Sciences
Publish Date:2014
Volume/Page:13(8):35-44.
Type:Human Study, Epidemiology
Categories:Bones/Joints, Arthritis, Bone Strength, Skeletal Fluorosis, Dental Fluorosis

• Acetylcholinesterase activity in fluorosis adversely affects mental well-being: an experimental study in rural Rajasthan
Author:Singh VP, Chauhan DS, Tripathi S, Gaur V, Tomar A, Tiwari M.
Journal Name:European Academic Journal
Publish Date:July 2014
Volume/Page:2(4):5857-5869.
Type:Human Study, Epidemiology
Categories:Brain, Brain Cellular/Tissue Effects, Cognitive Function, Cholinesterase, IQ Score

• Assessment of intelligence quotient among schoolchildren of fishermen community of Kutch, Gujarat, India
Author:Asawa K, Pujara P, Thakkar JP, Pandya BG, Sharma AR, Pareek S, Tak A, Tak M, Maniar R.
Journal Name:International Maritime Health
Publish Date:2014
Volume/Page:65(2):73-78.
Type:Human Study, Epidemiology
Categories:Brain, Cognitive Function, Dental Fluorosis, IQ Score

• Early diagnosis and complete recovery from fluorosis through practice of interventions
Author:Susheela AK, Mondal NK, Tripathi N, Gupta R.
Journal Name:Journal of the Association of Physicians of India
Publish Date:July 2014
Volume/Page:62:572-79.
Type:Human Study, Case Report
Categories:Bones/Joints, Arthritis, Skeletal Fluorosis, Gastrointestinal, Anti-Oxidants, Nutritional Status

• Haematological changes in fluorotic adults and children in fluoride endemic regions of Gaya district, Bihar, India.
Author:Yasmin S, Ranjan S, D’Souza D.
Journal Name:Environmental Geochemistry and Health
Publish Date:June 2014
Volume/Page:36(3):421-25.
Type:Human Study
Categories:Blood, Gastrointestinal

• Update on uncertain etiology of chronic kidney disease in Sri Lanka’s north-central dry zone
Author:Wanigasuriya K.
Journal Name:MEDICC Review
Publish Date:April 2014
Volume/Page:16(2):61-65.
Type:Human Study, Epidemiology
Categories:Kidney, Nephrotoxicity, Chemical Co-Exposures

• Cytogenetic analysis of human lymphocytes of fluorosis-affected men from the endemic fluorosis region in Nalgonda district of Andhra Pradesh, India
Author:Pawar AC, Naik SJK, Kumari SA.
Journal Name:Fluoride
Publish Date:January-March 2014
Volume/Page:47(1):78-84
Type:Human Study
Categories:Cancer, Genotoxicity, Sister chromatid exchange

• Skeletal fluorosis in relation to drinking water, nutritional status and living habits in rural areas of Maharashtra, India
Author:Dhurvey V, Dhawas S.
Journal Name:Journal of Environmental Science, Toxicology and Food Technology
Publish Date:February 2014
Volume/Page:8(1):63-67
Type:Human Study
Categories:Bones/Joints, Arthritis, Skeletal Fluorosis, Susceptible Populations, Nutritional Status, Sources of Exposure, Tea

• Arsenic and fluoride co-exposure affects the expression of apoptotic and inflammatory genes and proteins in mononuclear cells from children
Author:Estrada-Capetillo BL, Ortiz-Pérez MD, Salgado-Bustamante M, Calderón-Aranda E, Rodríguez-Pinal CJ, Reynaga-Hernández E, Corral-Fernández NE, González-Amaro R, Portales-Pérez DP.
Journal Name:Mutation Research
Publish Date:January 21, 2014
Volume/Page:S1383-5718(14)00007-2. doi: 10.1016/j.mrgentox.2014.01.006. [Epub ahead of print]
Type:Human Study
Categories:Blood, Immune System, Mechanisms of Cellular Toxicity, Apoptosis, Susceptible Populations, Chemical Co-Exposures,Arsenic

• Multiple painless masses: periostitis deformans secondary to fluoride intoxication
Author:Chitkara M, Rackoff PJ, Beltran LS.
Journal Name:Skeletal Radiology
Publish Date:December 19, 2013
Volume/Page:[Epub ahead of print]
Type:Human Study, Case Report
Categories:Bones/Joints, Skeletal Fluorosis, Differential Diagnosis, Sources of Exposure

• Comparative evaluation of serum fluoride levels in patients with and without chronic abdominal pain.
Author:Chahal A, Bala M, Dahiya RS, Ghalaut VS.
Journal Name:Clinica Chimica Acta
Publish Date:Dec. 4, 2013
Volume/Page:Dec 4. [Epub ahead of print]
Type:Human Study
Categories:Gastrointestinal

• Effect of fluoride on oxidative stress and biochemical markers of bone turnover in postmenopausal women
Author:Gondu AS, Naidu MD.
Journal Name:Fluoride
Publish Date:October-December 2013
Volume/Page:46(4):208–211.
Type:Human Study, Epidemiology
Categories:Bones/Joints, Mechanisms of Cellular Toxicity, Oxidative Stress, Age

• Effect of excess fluoride ingestion on human thyroid function in Gaya region, Bihar, India.
Author:Yasmin S, Ranjan S, uddin H, D'Souza D.
Journal Name:Toxicological & Environmental Chemistry
Publish Date:September 25, 2013
Volume/Page:[Epub ahead of print]
Type:Human Study, Epidemiology
Categories:Thyroid Gland, Thyroid Hormones

• Spirometry changes due to prolonged exposure to high level of fluoride in drinking water
Author:Saifullah N, Ahmed I, Qayyum S, Khan N, Khanm MH.
Journal Name:European Respiratory Journal
Publish Date:September 1, 2013
Volume/Page:42(Supp 57):1017.
Type:Human Study, Epidemiology
Categories:Bones/Joints, Skeletal Fluorosis, Lung

• Excessive iodine intake, water chemicals and endemic goitre in a Sudanese coastal area
Author:Medani AM, Elnour AA, Saeed AM.
Journal Name:Public Health Nutrition
Publish Date:September 2013
Volume/Page:16(9):1586-92.
Type:Human Study, Epidemiology
Categories:Thyroid Gland, Goiter

• Comparative assessment of intelligence quotient among children living in high and low fluoride areas of Kutch, India: a pilot study
Author:Nagarajappa R, Pujara P, Sharda AJ, Asawa K, Tak M, Aapaliya P, Bhanushali N.
Journal Name:Iranian Journal of Public Health
Publish Date:August 2013
Volume/Page:42(8):813-18.
Type:Human Study, Epidemiology
Categories:Brain, Cognitive Function, IQ Score

• Oxidative burden and altered trace elements as a biomarker of excessive endemic fluoride exposure in school children of eastern region in Rajasthan India
Author:Pratap SV, Singh CD, Sandeep T, Sandeep K, Mukesh T, Anurag T.
Journal Name:International Research Journal of Biological Sciences
Publish Date:May 2013
Volume/Page:2(5):54-58.
Type:Human Study
Categories:Mechanisms of Cellular Toxicity, Oxidative Stress

• Dose effect relationship between high fluoride intake and biomarkers of lipid metabolism in endemic fluorosis
Author:Bhardwaj M, Shashi A.
Journal Name:Biomedicine & Preventive Medicine
Publish Date:April-June 2013
Volume/Page:3(2):121-27.
Type:Human Study, Epidemiology
Categories:Heart, Mechanisms of Cellular Toxicity, Oxidative Stress, Cholesterol, Dose Response

• An epidemiological study of skeletal fluorosis in some villages of Chandrapur District, Maharashtra, India
Author:Sonali D, Varsha D, Jaya K, Rashmi U.
Journal Name:Journal of Environmental Research and Development
Publish Date:April-June 2013
Volume/Page:7(4A):1679-83.
Type:Human Study, Epidemiology
Categories:Bones/Joints, Arthritis, Skeletal Fluorosis

• Evaluation of total oxidative status and total antioxidant capacity in patients with endemic fluorosis
Author:Varol E, Icli A, Aksoy F, Bas HA, Sutcu R, Ersoy IH, Varol S, Ozaydin M.
Journal Name:Toxicology and Industrial Health
Publish Date:March 2013
Volume/Page:29(2):175-80.
Type:Human Study
Categories:Mechanisms of Cellular Toxicity, Oxidative Stress, Skeletal Fluorosis

• Prevalence and aetiology of juvenile skeletal fluorosis in the south-west of the Hai district, Tanzania–a community-based prevalence and case-control study
Author:Jarvis HG, Heslop P, Kisima J, Gray WK, Ndossi G, Maguire A, Walker RW.
Journal Name:Tropical Medicine & International Health
Publish Date:February 2013
Volume/Page:18(2):222-9.
Type:Human Study, Epidemiology
Categories:Bones/Joints, Skeletal Fluorosis, Susceptible Populations, Nutritional Status, Calcium, Protein, Rickets

• [The influence of high fluoride exposure in drinking water on endocrine hormone in female].
Author:Hou JX, Yang YJ, Gong B, Li SH, Ding Z, Wen SB, Li SQ, Cheng XM, Cui LX, Ba Y.
Journal Name:Zhonghua Yu Fang Yi Xue Za Zhi.
Language:Chinese (with English summary)
Publish Date:February 2013
Volume/Page:47(2):142-6.
Type:Human Study, Epidemiology
Categories:Reproductive Toxicity

• Clinical and biochemical profile of deiodinase enzymes and thyroid function hormones in patients of fluorosis
Author:Shashi A, Singla S
Journal Name:Australian Journal of Basic and Applied Sciences
Publish Date:2013
Volume/Page:7(4):100-107
Type:Human Study, Epidemiology
Categories:Thyroid Gland, Thyroid Hormones, Enzymes

• Endogenous and exogenous antioxidants status in seminal plasma of skeletal fluorotic patients
Author:Chauhan DS, Tomar A, Tiwari M, Singh VS, Tomar S, Tripathi S.
Journal Name:Scholars Journal of Applied Medical Sciences
Publish Date:2013
Volume/Page:1(3):152-57.
Type:Human Study
Categories:Mechanisms of Cellular Toxicity, Oxidative Stress, Susceptible Populations, Nutritional Status, Anti-Oxidants, Skeletal Fluorosis, Vitamin A, Vitamin C, Vitamin E

• MRI features of spinal fluorosis: results of an endemic community screening
Author:Ahmed I, Sohail S, Hussain M, Khan N, Khan MH.
Journal Name:Pakistan Journal of Medical Sciences
Publish Date:January 2013
Volume/Page:29(1):177-80.
Type:Human Study
Categories:Bones/Joints, Skeletal Fluorosis

• Increased plasma neopterin and hs-CRP levels in patients with endemic fluorosis
Author:Varol E, Aksoy F, Icli A, Arslan A, Yuksel O, Ersoy IH, Varol S, Dogan A.
Journal Name:Bulletin of Environmental Contamination and Toxicology
Publish Date:November 2012
Volume/Page:89(5):931-6.
Type:Human Study
Categories:Immune System, Skeletal Fluorosis

• Genotoxic damage in oral epithelial cells induced by fluoride in drinking-water on students of Tula de Allende, Hidalgo, Mexico
Author:Vazquez-Alvarado P, Melendez-Ocampo A, Ortiz-Espinosa RM, Munoz-Juarez S, Hernandez-Ceruelos A.
Journal Name:Journal of Toxicology and Environmental Health Sciences
Publish Date:October 2012
Volume/Page:4(8):123-129
Type:Human Study, Epidemiology
Categories:Cancer, Genotoxicity, Oral Mucosa

• Correlation of fluoride in drinking water with urine, blood plasma, and serum fluoride levels of people consuming high and low fluoride drinking water in Pakistan.
Author:Ahmed I, Rafique T, Hasan SK, Khan N, Khan MH, Usmani TH.
Journal Name:Fluoride
Publish Date:October-December 2012
Volume/Page:45(4):384–388.
Type:Human Study, Case Report
Categories:Susceptible Populations, Serum-F, Urine-F

• Effect of fluoride on reactive oxygen species and bone metabolism in postmenopausal women.
Author:Ravula S, Harinarayan CV, Prasad UV, Ramalakshmi T, Rupungudi A, Madrol V.
Journal Name:Fluoride
Publish Date:April-June 2012
Volume/Page:45(2):108–115.
Type:Human Study
Categories:Bones/Joints, Bone Mineralization/Quality, Susceptible Populations, Nutritional Status, Calcium, Serum-F, Tissue F Levels, Urine-F, Vitamin C, Vitamin D, Postmenopausal
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• Study of thyroid hormones free triiodothyronine (FT3), free thyroxine (FT4) and thyroid stimulating hormone (TSH) in subjects with dental fluorosis
Author:Hosur MB, Puranik RS, Vanaki S, Puranik SR.
Journal Name:European Journal of Dentistry
Publish Date:April 2012
Volume/Page:6(2):184-90.
Type:Human Study, Epidemiology
Categories:Thyroid Gland, Thyroid Hormones

• Effect of fluoride on reactive oxygen species and bone metabolism in postmenopausal women.
Author:Ravula S, Harinarayan CV, Prasad UV, Ramalakshmi T, Rupungudi A, Madrol V.
Journal Name:Fluoride
Publish Date:April-June 2012
Volume/Page:45(2):108–115.
Type:Human Study
Categories:Bones/Joints, Bone Mineralization/Quality, Susceptible Populations, Nutritional Status, Calcium, Serum-F, Tissue F Levels, Urine-F, Vitamin C, Vitamin D, Postmenopausal
, Infants, Sources of Exposure, Infant Formula/Foods

• Health problems in fluoride endemic areas of Gaya District
Author:Ranjan S, Yasmin S.
Journal Name:Ecoscan
Publish Date:2012
Volume/Page:1:237-42.
Type:Human Study, Epidemiology
Categories:Blood, Bones/Joints, Skeletal Fluorosis, Brain, Neurological Symptoms, Gastrointestinal, Glucose

• Environmental fluoride exposure and reproductive hormones in male living in endemic fluorosis villages in China
Author:Zhou T, Duan LJ, Ding Z, Yang RP, Li SH, Xi Y, Cheng XM, Hou JX, Wen SB, Chen J, Cui LX, Ba Y.
Journal Name:Life Science Journal
Publish Date:2012
Volume/Page:9(4):1-7.
Type:Human Study, Epidemiology
Categories:Reproductive Toxicity, Testosterone

• Serum fluoride and sialic acid levels in osteosarcoma
Author:Sandhu R, Lal H, Kundu ZS, Kharb S.
Journal Name:Biological Trace Element Research
Publish Date:December 2011
Volume/Page:144(1-3):1-5.
Type:Human Study
Categories:Cancer, Bone Cancer, Osteosarcoma

• Serum copper, zinc, and magnesium levels in patients with chronic fluorosis
Author:Ersoy IH, Koroglu BK, Varol S, Ersoy S, Varol E, Aylak F, Tamer MN.
Journal Name:Biological Trace Element Research
Publish Date:November 2011
Volume/Page:143(2):619-24.
Type:Human Study
Categories:Magnesium, Skeletal Fluorosis, Zinc

• Apoptosis of peripheral blood mononuclear cells in children exposed to arsenic and fluoride
Author:Rocha-Amador DO, Calderón J, Carrizales L, Costilla-Salazar R, Pérez-Maldonado IN.
Journal Name:Environmental Toxicology and Pharmacology
Publish Date:November 2011
Volume/Page:32(3):399-405.
Type:Human Study, Epidemiology
Categories:Immune System, Susceptible Populations, Chemical Co-Exposures, Apoptosis, Arsenic

• Chronic fluoride exposure has a role in etiology of coronary artery ectasia: sialic acid/glycosaminoglycan ratio
Author:Dede O, Varol E, Altinbas A, Varol S.
Journal Name:Biological Trace Element Research
Publish Date:November 2011
Volume/Page:143(2):695-701.
Type:Human Study
Categories:Heart

• Study on blood biochemical diagnostic indices for hepatic function biomarkers in endemic skeletal fluorosis
Author:Shashi A, Bhardwaj M.
Journal Name:Biological Trace Element Research
Publish Date:November 2011
Volume/Page:143(2):803-14.
Type:Human Study, Epidemiology
Categories:Bones/Joints, Bone Cells, Liver, Enzymes, Osteoblasts

• Morphometry of buccal mucosal cells in fluorosis–a new paradigm
Author:Rao SM, Sherlin HJ, Anuja N, Pratibha R, Priya P, Chandrasekar T.
Journal Name:Human & Experimental Toxicology
Publish Date:November 2011
Volume/Page:30(11):1761-8.
Type:Human Study, Epidemiology
Categories:Mechanisms of Cellular Toxicity, Apoptosis, DNA effects, Oxidative Stress, Genotoxicity, Oral Mucosa

• Analysis of children’s serum fluoride levels in relation to intelligence scores in a high and low fluoride water village in China.
Author:Xiang Q, Liang Y, Chen B, Chen L.
Journal Name:Fluoride
Publish Date:October-December 2011
Volume/Page:44(4):191–194.
Type:Human Study
Categories:Cognitive Function, IQ Score, Serum-F

• Association of dental fluorosis with polymorphisms of estrogen receptor gene in Chinese children.
Author:Ba Y, Zhang H, Wang G, Wen S, Yang Y, Zhu J, Ren L, Yang R, Zhu C, Li H, Cheng X, Cui L.
Journal Name:Biological Trace Element Research
Publish Date:October 2011
Volume/Page:143(1):87-96.
Type:Human Study, Case Report
Categories:Dental Fluorosis, Susceptible Populations, Genetics

• Serum parathyroid hormone levels in chronic endemic fluorosis.
Author:Koroglu BK, Ersoy IH, Koroglu M, Balkarli A, Ersoy S, Varol S, Tamer MN.
Journal Name:Biological Trace Element Research
Publish Date:October 2011
Volume/Page:143(1):79-86.
Type:Human Study
Categories:Parathyroid Gland, Hyperparathyroidism

• Relation between dental fluorosis and intelligence quotient in school children of Bagalkot district.
Author:Shivaprakash PK, Ohri K, Noorani H.
Journal Name:Journal of Indian Society of Pedodontics and Preventive Dentistry
Publish Date:September 2011
Volume/Page:29(2):117-120.
Type:Human Study
Categories:Brain, Cognitive Function, IQ Score

Author:Gurumurthy SM, Mohanty S, Bhongir AV, Mishra AK, Rao P.
Journal Name:International Journal of Medicine and Public Health
Publish Date:April-June 2011
Volume/Page:1(2):13-17
Type:Human Study, Epidemiology
Categories:Fetal Toxicity & Teratology, Pre-term/Low Weight Births, Infants

• Intelligence quotient of 7 to 9 year-old children from an area with high fluoride in drinking water.
Author:Poureslami HR, Horri A, Khoramian S, Garrusi B.
Journal Name:Journal of Dentistry and Oral Hygiene
Publish Date:April 2011
Volume/Page:3(4):61-64.
Type:Human Study
Categories:Brain, Cognitive Function, IQ Score

Effect of fluoride exposure on different immune parameters in humans
Author:Hernández-Castro B, Vigna-Pérez M, Doníz-Padilla L, Ortiz-Pérez MD, Jiménez-Capdeville E, González-Amaro R, Baranda L.
Journal Name:Immunopharmacology and Immunotoxicology
Publish Date:March 2011
Volume/Page:33(1):169-77.
Type:Human Study
Categories:Immune System

• The relationships between low levels of urine fluoride on children’s intelligence, dental fluorosis in endemic fluorosis areas in Hulunbuir, Inner Mongolia, China.
Author:Ding Y, Yanhui G, Sun H, Han H, Wang W, Ji X, Liu X, Sun D.
Journal Name:Journal of Hazardous Materials
Publish Date:February 2011
Volume/Page:186(2-3):1942-1946.
Type:Human Study
Categories:Brain, Cognitive Function, IQ Score

• Dose-dependent Na and Ca in fluoride-rich drinking water–another major cause of chronic renal failure in tropical arid regions
Author:Chandrajith R, Dissanayake CB, Ariyarathna T, Herath HM, Padmasiri JP.
Journal Name:The Science of the Total Environment
Publish Date:January 15, 2011
Volume/Page:409(4):671-5.
Type:Human Study
Categories:Kidney, Nephrotoxicity

• Effect of fluorozis [sic] on the erythrocyte antioxidant enzyme activity levels
Author:Akdogan M, Yilmaz D, Yontem M, Kaleli S, Kilic I.
Journal Name:Journal of the Chemical Society of Pakistan
Publish Date:2011
Volume/Page:33(5):646-51.
Type:Human Study
Categories:Mechanisms of Cellular Toxicity, Enzymes, Oxidative Stress

• Comparison of two village primary schools in northern Tanzania affected by fluorosis
Author:Shorter JP, Massawe J, Parry N, Walker RW.
Journal Name:International Health
Publish Date:December 2010
Volume/Page:2(4):269-74.
Type:Human Study, Epidemiology
Categories:Bones/Joints, Skeletal Fluorosis, Susceptible Populations, Genetics, Nutritional Status, Calcium, Genu Valgum

• Effect of endemic fluorosis on hematological parameters
Author:Ersoy IH, Alanoglu EG, Koroglu BK, Varol S, Akcay S, Ugan Y, Ersoy S, Tamer MN.
Journal Name:Biological Trace Element Research
Publish Date:December 2010
Volume/Page:138(1-3):22-7.
Type:Human Study, Epidemiology
Categories:Blood

• Fluoride consumption: the effect of water fluoridation.
Author:Mansfield P.
Journal Name:Fluoride
Publish Date:October-December 2010
Volume/Page:43(4):223–231.
Type:Human Study
Categories:Total Body Burden, Daily Intake Estimations, Urine-F

• A survey of goiter morbidity in Ban Mae Toen, Northwest Thailand
Author:McGlashan N, Chelkowska E, Sasananan S.
Journal Name:Southeast Asian Journal of Tropical Medicine and Public Health
Publish Date:September 2010
Volume/Page:41(5):1200-8.
Type:Human Study, Epidemiology
Categories:Thyroid Gland, Goiter

• Osteo-dental fluorosis in relation to age and sex in tribal districts of Rajasthan, India.
Author:Choubisa SL, Choubisa L, Choubisa D.
Journal Name:Journal of Environmental Science & Engineering
Publish Date:July 2010
Volume/Page:52(3):199-204.
Type:Human Study
Categories:Skeletal Fluorosis

• Differences in exposure and biological markers of fluoride among White and African American children
Author:Martinez-Mier EA, Soto-Rojas AE.
Journal Name:Journal of Public Health Dentistry
Publish Date:Summer 2010
Volume/Page:70(3):234-40.
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Prevalence, Susceptible Populations, Race/Ethnicity

• Effective interventional approach to control anaemia in pregnant women
Author:Susheela AK, Mondal NK, Gupta R, Ganesh K, Brahmankar S, Bhasin S, Gupta G.
Journal Name:Current Science
Publish Date:May 25, 2010
Volume/Page:98(10):1320-30.
Type:Human Study
Categories:Blood, Fetal Toxicity & Teratology, Pre-term/Low Weight Births, Susceptible Populations, Nutritional Status, Calcium,Infants, Iron, Vitamin C, Vitamin E, Anemia

• Impact of chronic fluorosis on left ventricular diastolic and global functions.
Author:Varol E, Akcay S, Ersoy IH, Koroglu BK, Varol S.
Journal Name:The Science of the Total Environment
Publish Date:May 1, 2010
Volume/Page:408(11):2295-8.
Type:Human Study, Case Report
Categories:Heart, ECG Abnormalities
Categories:Bones/Joints, Skeletal Fluorosis, Susceptible Populations, Nutritional Status, Anti-Oxidants, Genu Valgum

• Anemia in pregnancy: an easily rectifiable problem.
Author:Susheela AK.
Journal Name:Fluoride | Guest editorial
Publish Date:April-June 2010
Volume/Page:43(2):104–107.
Type:Human Study
Categories:Blood, Sources of Exposure, Anemia, Pregnancy, Premature birth

• Serum calciotropic hormone levels, and dental fluorisis in children exposed to different concentrations of fluoride and iodine in drinking water
Author:Ba Y, Zhu JY, Yang YJ, Yu B, Huang H, Wang G, Ren LJ, Cheng XM, Cui LX, Zhang YW.
Journal Name:Chinese Medical Journal
Publish Date:March 20, 2010
Volume/Page:123(6):675-679.
Type:Human Study, Epidemiology
Categories:Susceptible Populations, Nutritional Status, Calcium, Iodine

• Fluoride and health hazards: community perception in a fluorotic area of central Rajasthan (India): an arid environment
Author:Hussain 1, Hussain I, Sharma KC.
Journal Name:Environmental Monitoring and Assessment
Publish Date:March 2010
Volume/Page:162(1-4):1-14.
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Skeletal Fluorosis, Occupational-related difference, Sex-related difference

• Investigation and Analysis of Children’s IQ and Dental Fluorosis in a High Fluoride Area
Author:Li X, Hou G, Yu B, Yuan C, Liu Y, Hao Z.
Journal Name:Journal of Medical Pest Control
Publish Date:March 2010
Volume/Page:26(3): 230-231.
Type:Human Study
Categories:Brain, Cognitive Function, IQ Score

• Serum ionic fluoride concentrations are related to renal function and menopause status but not to age in a Japanese general population
Author:Itai K, Onoda T, Nohara M, Ohsawa M, Tanno K, Sato T, Kuribayashi T, Okayama A.
Journal Name:Clinica Chimica Acta
Publish Date:February 2010
Volume/Page:411(3-4):263-6.
Type:Human Study
Categories:Kidney, Risks to Kidney Patients, Total Body Burden, Tissue F Levels, Serum-F

• Electrocardiographic evaluation in patients with endemic fluorosis without clinically evident heart disease
Author:Varol E, Akçay S, Ersoy YE, Özaydyn M, Koroglu BK, Varol S.
Journal Name:S.D.Ü. Typ Fak. Derg
Publish Date:2010
Volume/Page:17(4):9-14.
Type:Human Study, Epidemiology
Categories:Heart, ECG Abnormalities

• Relationship between municipal water fluoridation and preterm birth in Upstate New York
Author:Hart R, Feelemyer J, Gray C, Lodise T, Patel N, Wymer S, McNutt LA.
Journal Name:Abstract presented at American Public Health Association
Publish Date:November 7-9, 2009
Volume/Page:n/a
Type:Human Study, Epidemiology
Categories:Fetal Toxicity & Teratology, Pre-term/Low Weight Births, Reproductive Toxicity, Susceptible Populations, Race/Ethnicity

• Associations of fluoride intake with children’s bone measures at age 11.
Author:Levy SM, Eichenberger-Gilmore J, Warren JJ, Letuchy E, Broffitt B, Marshall TA, Burns T, Willing M, Janz K, Torner JC.
Journal Name:Community Dentistry and Oral Epidemiology
Publish Date:October 2009
Volume/Page:37(5):416-26.
Type:Human Study, Clinical Trial
Categories:Bones/Joints, Bone Density, Bone Mineralization/Quality, Total Body Burden, Daily Intake Estimations, Sources of Exposure, Age, Sex-related difference

• Oxidative stress in cases of chronic fluoride intoxication
Author:Ailani V, Gupta RC, Gupta SK, Gupta K.
Journal Name:Indian Journal of Clinical Biochemistry
Publish Date:October 2009
Volume/Page:24(4):426-9.
Type:Human Study
Categories:Susceptible Populations, Nutritional Status, Calcium, Oxidative Stress, Vitamin C, Vitamin D

• Prevalence and manifestations of water-born fluorosis among schoolchildren in Kaiwara village of India: a preliminary study
Author:Isaac A, Silvia WD, Somanna SN, Mysorekar V, Narayana K, Srikantaiah P.
Journal Name:Asian Biomedicine
Publish Date:October 2009
Volume/Page:3(5):563-66.
Type:Human Study, Epidemiology
Categories:Thyroid Gland, Goiter, Genu Valgum

• Skeletal fluorosis causing high cervical myelopathy
Author:Kumar H, Boban M, Tiwari M.
Journal Name:Journal of Clinical Neuroscience
Publish Date:June 2009
Volume/Page:6(6):828-30.
Type:Human Study, Case Report
Categories:Bones/Joints, Skeletal Fluorosis, Spinal Cord Compression

• Serum osteocalcin and calcitonin in adult males with different fluoride exposures
Author:Ma J, Li M, Song Y, Tu J, Liu F, Liu K.
Journal Name:Fluoride
Publish Date:April-June 2009.
Volume/Page:42(2):133–136.
Type:Human Study, Epidemiology
Categories:Bones/Joints, Skeletal Fluorosis

• The relationships between two different drinking water fluoride levels, dental fluorosis and bone mineral density of children.
Author:Grobler SR, Louw AJ, Chikte UM, Rossouw RJ, van W Kotze TJ.
Journal Name:The Open Dentistry Journal
Publish Date:April-June 2009
Volume/Page:3;3:48-54.
Type:Human Study, Epidemiology
Categories:Dental Fluorosis, Susceptible Populations, Age, Bone Density, Bone Mineralization/Quality, Sex-related difference

• Effect of fluoride exposure on Intelligence Quotient (IQ) among 13-15 year old school children of known endemic area of fluorosis, Nalgonda District, Andhra Pradesh.
Author:Sudhir KM, Chandu GN, Prashant GM, Reddy VVS .
Journal Name:Journal of the Indian Association of Public Health Dentistry
Publish Date:2009
Volume/Page:(13):88-94.
Type:Human Study
Categories:Brain, Cognitive Function, IQ Score

• Influence of raised fluorine concentrations in water on structurally-functional state of bone mass, teeth, anthropometric parameters and physical development of teenagers
Author:Povoroznyuk VV, Grygoreva NV, Vilensky AV, Dmitrenco OP.
Journal Name:Bone
Publish Date:2009
Volume/Page:45:S76.
Type:Human Study, Epidemiology
Categories:Bones/Joints, Bone Density, Susceptible Populations, Nutritional Status, Protein

• Elevated levels of arsenic and fluoride, but not selenium, associated with endemic disease in the Chinese village of Dazhuyuan, Shaanxi province.
Author:Wang Z, Guo X, Bai G, Lei Y, Wang Y, Fan Z, Zhang Q, Ding Y.
Journal Name:Fluoride
Publish Date:January-March 2009
Volume/Page:2(1):34–38.
Type:Human Study, Epidemiology
Categories:Total Body Burden, Daily Intake Estimations, Chemical Co-Exposures, Serum-F, Urine-F, Food-F, Hair-F, Selenium,Soil-F

• Neurology of endemic skeletal fluorosis
Author:D. Raja Reddy
Journal Name:Neurology India
Publish Date:January-February 2009
Volume/Page:57(1):7-12
Type:Human Study, Epidemiology
Categories:Bones/Joints, Skeletal Fluorosis, Radiographic Appearance

• COL1A2 gene polymorphisms (Pvu II and Rsa I), serum calciotropic hormone levels, and dental fluorosis.
Author:Huang H, Ba Y, Cui L, Cheng X, Zhu J, Zhang Y, Yan P, Zhu C, Kilfoy B, Zhang Y.
Journal Name:Community Dentistry and Oral Epidemiology
Publish Date:December 2008
Volume/Page:36(6):517-22.
Type:Human Study
Categories:Dental Fluorosis, Susceptible Populations, Genetics

• Pharmacokinetics of ingested fluoride: lack of effect of chemical compound
Author:Whitford GM, Sampaio FC, Pinto CS, Maria AG, Cardoso VE, Buzalaf MA.
Journal Name:Archives of Oral Biology
Publish Date:November 2008
Volume/Page:53(11):1037-41.
Type:Human Study
Categories:Silicofluorides, Pharmacokinetics

• Incidence of skeletal deformities in endemic fluorosis.
Author:Shashi A, et al.
Journal Name:Tropical Doctor
Publish Date:October 2008
Volume/Page:38(4):231-233.
Type:Human Study
Categories:Bones/Joints, Skeletal Fluorosis, Sex-related difference

• Changes in serum seromucoid following compensatory hyperparathyroidism: A sequel to chronic fluoride ingestion
Author:Gupta SK, Gupta RC, Gupta K, Trivedi HP.
Journal Name:Indian Journal of Clinical Biochemistry
Publish Date:April 2008
Volume/Page:23(2):176-80.
Type:Human Study, Epidemiology
Categories:Parathyroid Gland, Hyperparathyroidism

• Nutritional bone disease in Indian population
Author:S Teotia SP, Teotia M.
Journal Name:The Indian Journal of Medical Research
Publish Date:March 2008
Volume/Page:127(3):219-28.
Type:Human Study, Epidemiology
Categories:Bones/Joints, Osteomalacia, Skeletal Fluorosis, Susceptible Populations, Nutritional Status, Calcium, Rickets, Vitamin D

• Fluoride and endemic fluorosis in the Karbianglong District, Assam, India
Author:Kotoky P, Barooah PK, Baruah MK, Goswami A, Borah GC, Gogoi HM, Ahmed F, Gogoi A, Paul AB.
Journal Name:Fluoride
Publish Date:January-March 2008
Volume/Page:41(1):42–45.
Type:Human Study, Epidemiology
Categories:Bones/Joints, Skeletal Fluorosis, Osteo-dental fluorosis

• Dyspepsia associated with fluoridated water
Author:Spittle B.
Journal Name:Fluoride
Publish Date:January-April 2008
Volume/Page:41(1):89-92.
Type:Human Study, Case Report
Categories:Gastrointestinal, Susceptible Populations, Hypersensitivity

• Correlation between serum fluoride and hyperglycemia in endemic fluorosis area
Author:Pujary UR, Rao P, Mohanthy S, Krishna R, Reddy D.
Journal Name:Indian Journal of Clinical Biochemistry
Publish Date:December 2007
Volume/Page:22(Suppl):383.
Type:Human Study, Epidemiology
Categories:Diabetes, Glucose

• Confirmation of and explanations for elevated blood lead and other disorders in children exposed to water disinfection and fluoridation chemicals
Author:Coplan MJ, Patch SC, Masters RD, Bachman MS.
Journal Name:Neurotoxicology
Publish Date:September 2007
Volume/Page:28(5):1032-42.
Type:Human Study, Epidemiology, Review
Categories:Brain, Brain Cellular/Tissue Effects, Silicofluorides, Chemical Co-Exposures, Cholinesterase, Enzymes, Lead

• Enamel hypoplasia in children with renal disease in a fluoridated area
Author:Ibarra-Santana C, Ruiz-Rodríguez Mdel S, Fonseca-Leal Mdel P, Gutiérrez-Cantú FJ, Pozos-Guillén Ade J.
Journal Name:Journal of Clinical Pediatric Dentistry
Publish Date:Summer 2007
Volume/Page:31(4):274-8
Type:Human Study
Categories:Dental Fluorosis, Risk Factors, Kidney, Risks to Kidney Patients

• Osteosclerosis due to endemic fluorosis
Author:Tamer MN, Kale Koroglu B, Arslan C, Akdogan M, Koroglu M, Cam H, Yildiz M.
Journal Name:The Science of the Total Environment
Publish Date:February 1, 2007
Volume/Page:373(1):43-8.
Type:Human Study, Epidemiology
Categories:Bones/Joints, Skeletal Fluorosis, Differential Diagnosis

• Dose-effect relationship between drinking water fluoride levels and damage to liver and kidney functions in children
Author:Xiong X, Liu J, He W, Xia T, He P, Chen X, Yang K, Wang A.
Journal Name:Environmental Research
Publish Date:January 2007
Volume/Page:103(1):112-6.
Type:Human Study
Categories:Kidney, Nephrotoxicity

• Lipid peroxidation and antioxidant enzyme status of adult males with skeletal fluorosis in Andhra Pradesh, India.
Author:Kalyanalakshmi P, Vijayabhaskar M, Naidu MD.
Journal Name:Fluoride
Publish Date:January-March 2007
Volume/Page:40(1):42-45.
Type:Human Study, Epidemiology
Categories:Bones/Joints, Skeletal Fluorosis, Mechanisms of Cellular Toxicity, Enzymes, Oxidative Stress, Lipid peroxidation

• Recovery from skeletal fluorosis
Author:Cundy T.
Journal Name:Journal of Bone and Mineral Research
Publish Date:2007
Volume/Page:22(9):1475
Type:Human Study, Case Report
Categories:Bones/Joints, Skeletal Fluorosis, Treatment

• Fluoride aggravation of oxidative stress in patients with chronic renal failure.
Author:Bober J, Kwiatkowska E, Kedzierska K, Olszewska M, Stachowska E, Ciechanowski K, Chlubek D.
Journal Name:Fluoride
Publish Date:October-December 2006
Volume/Page:39(4):302–309.
Type:Human Study
Categories:Kidney, Risks to Kidney Patients, Dialysis, Oxidative Stress

• Fluorotoxic metabolic bone disease: an osteo-renal syndrome caused by excess fluoride ingestion in the tropics.
Author:Harinarayan CV, Kochupillai N, Madhu SV, Gupta N, Meunier PJ.
Journal Name:Bone
Publish Date:October 2006
Volume/Page:39(4):907-14.
Type:Human Study
Categories:Bones/Joints, Mechanism of Toxicity, Nephrotoxicity, Metabolic bone disease, Osteosclerosis, Tetany

• Variations in concentration of fluoride in blood plasma of pregnant women and their possible consequences for amelogenesis in a fetus.
Author:Opydo-Szymaczek J, Borysewicz-Lewicka M.
Journal Name:Homo (Journal of Comparative Human Biology)
Publish Date:August 2006
Volume/Page:57(4):295-307.
Type:Human Study, Case Report
Categories:Fetal Toxicity & Teratology, Total Body Burden, Tissue F Levels, Fluoride Supplements, Saliva/Plaque, Pregnant women

• Antioxidant defense systems in red blood cell lysates of men with dental fluorosis living in Tamil Nadu, India
Author:Shanthakumari D, Srinivasalu S, Subramanian S.
Journal Name:Fluoride
Publish Date:July-September 2006
Volume/Page:39(3):231-39.
Type:Human Study
Categories:Blood, Dental Fluorosis, Mechanisms of Cellular Toxicity, Oxidative Stress

Page reviewed: 4 July, 2017